Karen Read’s ‘20/20’ special airs Friday. Here’s what we know.

With her sensational murder case still dominating headlines as she inches closer to her second trial, Karen Read is set to appear in a new ABC “20/20” special airing Friday. 

The news program released a trailer on social media Tuesday, promising “exclusive personal video, one-on-one with Karen Read one week before her trial.” Some of the footage in the trailer appears to come from an interview Read gave to ABC’s “Nightline” last year, months before her trial.

Read, 44, is accused of drunkenly and deliberately backing her SUV into Boston Police Officer John O’Keefe — her boyfriend of two years — and leaving him to die in the snow outside a home in Canton in January 2022. Prosecutors allege Read’s deteriorating relationship with O’Keefe may have driven her to kill; they’ve pointed specifically to flirty texts she exchanged with another man, as well as the angry voicemails she left O’Keefe the morning he died, calling him a “f***ing pervert” and telling him she hated him. 

“Would you say that you were angry with John that night?” ABC News’s Matt Gutman asks Read in the “20/20” trailer.

“Yes,” Read replies frankly. 

But the Mansfield woman has steadfastly maintained her innocence, and her lawyers have pointed to a collection of civilian and law enforcement witnesses they say conspired to frame Read for O’Keefe’s death. 

“You’re alleging that they’re covering it up,” Gutman notes in the trailer. “Why would they want to be involved in this conspiracy?” 

“Because he’s dead,” Read fires back. 

Read’s first trial began in April and resulted in a mistrial on July 1 after the jury came back deadlocked. Prosecutors intend to retry her in January. 

The case drew national attention throughout more than eight weeks of testimony, with crowds gathering outside Norfolk Superior Court in Dedham each day of the trial. The “20/20” trailer includes clips of “Free Karen Read” supporters proclaiming Read’s innocence, as well as counterprotesters chanting “lock her up” and “Justice for JJ” — O’Keefe’s nickname.

Several of O’Keefe’s friends also make appearances in the trailer, reflecting on his memory or critiquing Read’s demeanor during the trial. Read, meanwhile, is shown getting ready for court, touching up her hair and makeup and double checking her outfit. 

“I’m confident I’m doing everything I can, and that includes looking professional for court,” she tells the camera. “I just got this suit from the tailor because the sleeves were too long and it’s a pet peeve of my mother’s to see people with sleeves that are too long.”

Read’s “20/20” special premieres Friday at 9 p.m. Eastern Standard Time. It will also be available to stream on Hulu.